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L'urbanisme, terme apparu récemment dans la langue (au début du XXe siècle), n'est pas aisé à définir. Il a suscité de nombreuses " théories " dont aucune n'a fait l'unanimité. Peut-être cette difficulté s'explique-t-elle par le caractère essentiellement pluridisciplinaire d'une activité qui vise à créer dans le temps une disposition ordonnée de l'espace, en recherchant harmonie, bien-être et économie. En effet, l'urbanisme relève autant de l'art que de l'architecture, de l'économie que de la sociologie, de l'histoire que de la géographie, du droit que de l'ingénierie. Quelle est l'histoire de l'urbanisme depuis son origine, et en quoi consiste concrètement sa pratique en France depuis les diverses lois qui ne cessent de se succéder et de complexifier sa pratique ?

Regional planning --- City planning

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What was the name of Led Zeppelin's airplane and how was it customised for the band? Why is there no 'a' in 'Led'? What led to the death of John Bonham? What has J.R.R. Tolkien got to do with the band? And which Japanese city awarded the band with a medal after they played a benefit gig there?This fantastic book features more than one hundred facts about Led Zeppelin, one of the most highly respected rock bands in history. With the facts separated into chapters covering the members of the band, its history, the albums and more, you are sure to learn some fascinating new information about the band. So whether you're a fan from back in the day or are only now beginning to appreciate classic rock music, this is the perfect book for you!.

Led Zeppelin (Musical group).

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L'inceste est un crime dans lequel baignent nombre de nos familles, dans lequel se vautre notre société. Ce livre ne cherche pas à se rajouter aux très bons ouvrages théoriques publiés sur ce sujet. Il cherche à utiliser l'expérience du dedans et du dehors, en tant qu'enfant abusé et en tant que thérapeute et thérapeute familiale de l'auteure, pour traquer au plus près le silence et le déni à l'intérieur de soi, au sein de la famille, au sein de nos familles, au coeur de notre société. Il cherche à donner du sens à une douloureuse expérience, à apporter une humble contribution au mouvement en marche. Celui qui permet peu à peu de mettre du poids dans la balance, de repousser le silence qui revient encore et toujours à la charge. Celui qui se tourne vers la vie, désireux que nos enfants vivent pleinement leur innocence, quitte à dénoncer les forfaits de nos vieillards et de nos morts. Ce livre retrace, à travers une histoire, à travers une déambulation dans les cavités d'une mémoire abimée, et à travers une expérience de thérapeute, le chemin tortueux de ceux qui tentent de démêler la toile complexe et piégeuse de l'inceste et du déni personnel, familial et sociétal. Il cherche à mettre du poids dans la balance, pour la guérison et la libération personnelle et transgénérationnelle, et contre l'oubli récurrent.

Inceste --- Dénégation (psychologie) --- Violences sexuelles --- Incest --- Psychic trauma --- Denial (Psychology) --- Sex crimes

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The Identification of the Genetic Components of Autism Spectrum Disorders 2019 will serve as a resource for laboratory and clinical scientists as well as translational-based researchers, primary healthcare providers or physicians, psychologists/psychiatrists, neurologists, developmental pediatricians, clinical geneticists, and other healthcare providers, teachers, caregivers and students involved in autism spectrum disorders (ASD) with the goal to translate information directly to the clinic, education and home setting. Other professionals, students and families might find this textbook of value based on better awareness, causes and understanding of genetic components leading to autism and open avenues for treatment. Genetics play a role with up to 90% of autism, with over 800 currently recognized genes contributing to causes, clinical presentation, treatment, and counseling of family members. This textbook includes 13 chapters divided into three sections (clinical, genetics, other) written by experts in the field dedicated to research and clinical care, description, treatment and generating relevant reviews for ASD and related disorders impacting gene expression, profiling, and pathways. Identification of potential risk factors will be discussed, including obesity, microbiota, malignancy, and the immune system, as well as their direct or indirect contribution to ASD treatment and causation.

Research & information: general --- Biology, life sciences --- Genetics (non-medical) --- autism spectrum disorders (ASD) --- cancer --- overlapping genes and gene profiling --- super-pathways --- phenotypes and diseases --- molecular functions and processes --- 15q11.2 BP1-BP2 microdeletion (Burnside-Butler) syndrome --- imprinting --- parent-of-origin effects --- phenotype-genotype correlation --- autism --- developmental delays --- motor delays --- microbiome --- gut --- ProSAP2 --- Phelan McDermid Syndrome --- gut–brain interaction --- leaky gut --- IL-6 --- SHANK --- collapsin response mediator protein 4 --- autism spectrum disorder --- neurodevelopmental disorder --- whole-exome sequencing --- animal model --- sex different phenotypes --- 15q11.2 BP1–BP2 microdeletion (Burnside–Butler syndrome) --- NIPA1 --- NIPA2 --- CYFIP1 --- TUBGCP5 genes --- Prader–Willi and Angelman syndromes --- magnesium transporters and supplementation --- potential treatment options --- intellectual disability --- AMPA receptors --- NMDA receptors --- guanine nucleotide exchange factor --- synaptic plasticity --- Autism spectrum disorder --- ASD --- Obesity --- Overweight --- Body mass index --- BMI --- autism candidate genes --- synaptotagmin-like protein 4 (SYTL4) --- transmembrane protein 187 (TMEM187) --- SYTL4-protein structure --- STRING-protein-protein interaction --- expression profile --- microRNA- interactions --- autism spectrum disorders --- biological networks --- genomics --- multi-omics --- network diffusion --- data integration --- genetics --- quantitative traits --- stratification by trait severity --- heterogeneity reduction --- case-control association analysis --- fragile X syndrome --- RNA toxicity --- DNA methylation --- mosaicism --- pediatrics --- MS-QMA --- AmplideX --- cytokine --- monocyte --- β-glucan --- T cell cytokine --- trained immunity --- maternal immune activation --- epigenetics --- mice --- postnatal VPA injection --- SAM --- gene expression --- nanostring

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